He studied Visual Arts in the National School of Painting, Sculpture and Engraving “La Esmeralda”.

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He has held various solo exhibitions both in Mexico and abroad, including:

Miradora, Atrio de San Francisco, Mexico City (2022); Hybrid times, Asphalt Festival, Düsseldorf (2022); El estado de las cosas, Museo del Chopo, Mexico City (2021); Te conozco de antes, Proyectos Monclova & Machete Gallery, Mexico City (2021) ;So it will be the past, Dot Fiftyone Gallery, Miami (2020); Tomorrow, ashes, Machete Gallery (2019), El Color del Sur, Machete Gallery, Mexico City (2017); Necessary Objects, Dot Fiftyone Gallery, Miami (2014); Future Ruins, Luis Adelantado Gallery, Mexico City (2013); Black Storms, El Clauselito, Museum of Mexico City, Mexico City (2012); Bestial Number, Museo Ex Teresa Arte Actual, Mexico City (2012); among other.

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Among his group exhibitions are included: OTRXS MUNDXS, Museo Tamayo, Mexico City (2020), 3rd Kamias Triennial, Manila, Philippines (2020); An exhibition with works by..., Kunstinstituut Melly, Rotterdam (2020); El animal herido, Museo Experimental El Eco, Mexico City (2019); Estudio de Trazo, Museo de Arte Moderno, Mexico City (2014); Panoramic, Palace of Fine Arts, Mexico City (2013); Mystic Route, Museum of Contemporary Art of Monterrey, Monterrey (2013); History of A, Amparo Museum, Puebla, Mexico (2011).

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He has twice received the Young Creators scholarship from the National Fund for Culture and the Arts (FONCA) in 2007 and 2014. He took part of the Casa Wabi (Puerto Escondido, Oaxaca, MX) residency in 2022, the BEMIS (Omaha, Nebraska, US) and Dedazo (Ejido Felipe Carrillo Puerto, Chiapas, MX) residencies in 2018, the Omi (NY, US) residency in 2015; in 2008 he participated in the 18th Street Arts Center in Los Angeles, USA; and completed the Skowhegan (Maine, USA residency) in 2016.

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He currently lives and works in Mexico City, where he is a founding member and co-director of the cultural space Obrera Centro.

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His work belongs to the following collections in Mexico City: Fundación JUMEX Collection, Museum of Modern Art, University Museum of Contemporary Art and Fundación Alumnos 47; in Puebla at the Museo Amparo, and in the United States it is part of the Perez Art Museum and Patricia Phelps de Cisneros collections.

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Marcos Castro is currently part of the National Creators System by FONCA.